Following a Radical Prostatectomy (RP) procedure - Erectile Dysfunction can begin immediately following the removal of the entire prostate and surrounding tissues, whether the nerve-sparing or non-nerve-sparing technique is used. If the nerve-sparing technique is used, recovery from Erectile Dysfunction may occur within the first year following the procedure. Recovery of erectile function after a non-nerve-sparing technique is unlikely but is possible.

Radiation Therapy - The onset of Erectile Dysfunction following radiation therapy is gradual and usually begins about six months following treatment. Without treatment for Erectile Dysfunction, ED is usually permanent.

Hormone Therapy - When hormone therapy is used, Erectile Dysfunction may occur approximately two to four weeks following the initiation of the therapy and is usually accompanied by a decreased desire for sex. Without any treatment, Erectile Dysfunction is usually permanent.